Drug-based compounds used as corrosion inhibitors for various metals in different corrosive media: A mini-review

Document Type : Review Article

Authors

1 Department of chemistry, Amirkabir University of Technology, Tehran, Iran

2 Department of Chemistry, University of New Brunswick, Fredericton, NB, E3B 5A3, Canada

10.22091/jaem.2025.13864.1031

Abstract

The deterioration of metallic materials and their alloys can be avoided through the application of electrochemical corrosion inhibitors. Due to the toxicological concerns, limited biodegradability, and high cost associated with many conventional corrosion inhibitors, there has been a growing interest in the development and application of more environmentally benign and sustainable alternatives. Among these, natural and synthetic pharmaceutical compounds have emerged as promising candidates. Accordingly, this study aims to highlight the potential of natural and synthetic drugs as effective, manageable, and eco-friendly solutions for mitigating metal corrosion. In this review paper, the drug-based corrosion inhibitor compounds used for different metals into various corrosive media are classified into several classes based on their pharmacological classification. The classifications are antibacterial drugs, cardiovascular drugs, autacoids and related drugs, hormones and related drugs, drugs acting on central nervous system, drugs for respiratory disorders, drugs affecting blood, and gastrointestinal drugs. In addition, these classifications are divided into some subclasses. The corrosion inhibition performances of these drug-based compounds are investigated, and the results are presented in the tables. The obtained results revealed that the drug-based compounds were economic, efficient, and environmentally friendly corrosion inhibitors, and they gave high inhibition efficiency. Moreover, at the end of the review paper, the inhibition mechanism of the drug-based compounds has been featured.

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