Biodegradable Gelatin-Based Silver Nanocomposite Hydrogels: Synthesis, Characterization, and Antibacterial Performance

Document Type : Review Article

Author

Department of Chemistry, Faculty of Sciences, Tabriz University, Tabriz, Iran

10.22091/jaem.2025.3811

Abstract

In this study, silver nanocomposite hydrogels were synthesized using acrylamide (AM) and biodegradable gelatin (GA) as the polymer matrix. Silver nanoparticles were generated in situ within the hydrogel network by introducing Ag⁺ ions followed by reduction with sodium borohydride. The influence of gelatin content on the swelling behavior of the hydrogels was systematically examined. Comprehensive characterization of the nanocomposites was carried out using Fourier-transform infrared spectroscopy (FTIR), UV–Vis spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), as well as scanning and transmission electron microscopy (SEM and TEM). The resulting gelatin-based silver nanocomposite hydrogels exhibited notable antibacterial activity, suggesting their strong potential for use in antimicrobial applications.

Keywords